Epidemiology of hiv-tuberculosis co-infection among patients on anti-retroviral therapy inSokoto state, Nigeria.
AbstractBackground: Human immunodeficiency virus/acquired immune deficiency syndrome and tuberculosis are commonly called the “deadly duo”, because human immunodeficiency virus increases susceptibility
to tuberculosis which inturn accelerates its progression to acquired immune deficiency syndrome. This study describes human immunodeficiency virus/ tuberculosis co-infection in Sokoto State, Nigeria. Methods: Data were extracted from medical records of human immunodeficiency virus infected patients on antiretroviral therapy in health facilities that offer comprehensive care for human immunodeficiency virus infected patients in Sokoto State, and analysed.
Results: Majority of the 353 study subjects were females (60.6%) aged 30-39 years (37.4%) and living in Sokoto state (78.5%). Care entry points were Medical Outpatient Department (36.8%), General
Outpatient Department (35.4%) and voluntary counseling centre (23.5%). Enrolment for human immunodeficiency virus care was highest in May (13.4%) and lowest in March (5.1%). The functional
status of majority (75.8%) of the study subjects was asymptomatic normal activity. Thirty-three (9.3%) of the study subjects were human immunodeficiency virus/Tuberculosis co-infected. Human immune
deficiency virus only cases and human immunodeficiency virus/Tuberculosis co-infected cases were similar with respect to age and sex but differed significantly with respect to WHO clinical stage, CD4 count and functional status. Conclusion: Human immunodeficiency virus only and human immunodeficiency virus/tuberculosis coinfection
cases have similar demographic characteristics but differ with respect to the stage of acquired immune deficiency syndrome.