Comparative evaluation of lignocaine and lignocainebupivacaine for lumbo-sacral epidural block in diazepam sedated West African dwarf goats

  • A.A. Lawan
  • F.B. Falade
  • A. Adetunji
Keywords: Bupivacaine, Epidural, Goats, Lignocaine, Loco-regional, Sedation


This study compared the onset of neural blockade, onset and duration of analgesia and duration of recumbency produced in five healthy West African Dwarf (WAD) goats by the lumbo-sacral epidural injections of a mixture of 2mg/kg lignocaine 2% solution and 0.95mg/kg bupivacaine 0.5% solution (LBM) and 4mg/kg lignocaine 2% solution. Associated changes in heart rate (HR), respiratory rate (RR) and rectal temperature (RT) were recorded at 10-min intervals in the initial 1 hour. The onset of neural blockade with LBM (9.6±2.7 min) was significantly (p<0.05) longer with LIG (2.8± 0.4 min) the onset (24.8 ± 3.8 min) and duration (113.8± 16.5 min) of analgesia with LBM were significantly (p<0.05) longer than the onset (11.6 ± 2.4min) and duration (68.6 ±14.9min) of analgesia with LIG respectively. The duration of recumbency with LBM (148.0 ± 9.7min) was also significantly (p<0.05) longer with LIG (81.6 ± 6.5). There were no significant differences (p>0.05) in the physiological parameters between the two groups. It was concluded that epidurally administered LBM had a slower onset of neural blockade but longer onset of analgesia, duration of analgesia and duration of recumbency than with LIG in diazepam-sedated goats. The epidural blockade also produced insignificant changes in the mean HR, RR, and RT responses of the experiment to both drug protocols.

Keywords: Bupivacaine, Epidural, Goats, Lignocaine; Loco-regional, Sedation


Journal Identifiers

eISSN: 1595-093X
print ISSN: 1595-093X