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Direct and simple approach for assigning absolute configuration in wedge dash projection


Sarika Malik
Shriniwas Gurjar
Sonia Ratnani

Abstract

The procedure of assignment of absolute configuration to optical stereoisomers in various projections has been already described in  literature. Most common methods utilize the Fischer Projection as the standard and hence demands a three dimensional structure (wedge dash projection, newmann projection, sawhorse projection) to be inter converted to two dimensional planar Fischer Projection. This adds on an extra exercise which may sometimes cause error while specifying Absolute Configuration to a molecule originally represented in  three dimensional projections. Hence this assignment of configuration to optical isomers should be directly taught to undergraduates through three dimensional representation of the molecule as stereochemistry deals with three dimensional aspects of an organic  compound. This method assigns absolute configuration to the chiral molecules directly in wedge dash projection without interconverting to Fischer Projection.


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eISSN: 2227-5835