<b>Efficient and convenient synthesis of symmetrical carboxylic anhydrides from carboxylic acids with sulfated zirconia by phase transfer catalysis</b>

Abstract

An efficient and convenient procedure for the synthesis of symmetrical carboxylic anhydrides from carboxylic acids with sulfated zirconia by PEG-1000 phase transfer catalysis has been developed. The reactions proceeded under mild and solvent-free conditions to provide the carboxylic anhydrides in good to excellent yields. The product can be isolated by a simple extraction with organic solvent, and the catalyst system can be recycled or reused without any significant loss of catalytic activity.

KEY WORDS: Carboxylic anhydrides, Carboxylic acids, SO₄^2-/ZrO₂, Phase transfer catalysis

Bull. Chem. Soc. Ethiop. 2011, 25(2), 255-262.