PROMOTING ACCESS TO AFRICAN RESEARCH

African Journal of Biotechnology

Log in or Register to get access to full text downloads.

Remember me or Register



Levels of inflammatory markers (complement C3, Complement C4 and C-reactive protein) in smokers

M Sanai, N Hussain

Abstract


The study aimed to discover the relative significance of selected inflammatory markers in smokers. Serum levels of complement C3, C4 and C-reactive protein were determined in 24 male smokers (18 to 73 years). A group of 24 healthy non-smokers was taken as control. C3 and C4 were measured by using radial immunodiffusion technique and CRP was determined by latex agglutination technique. The statistical analysis was done using Student’s t-test and Fisher exact test which were used for the comparison of the characteristics of the groups. C3 and C4 were observed to be 33.84 and 45.28% higher in smokers, respectively, but statistically insignificant as (p = 0.122) and (p = 0.078). No significant difference was observed in the case of C-reactive protein levels and the body mass index of smokers and non-smokers (CRP: p = 0.49 and BMI: p = 0.64). These findings repudiated the presence of an acute phase and inflammatory reaction in smokers.

Key words: Smokers, C-reactive protein, body mass index, complement.




AJOL African Journals Online