Factors associated with TB/HIV co-infection among drug sensitive tuberculosis patients managed in a secondary health facility in Lagos, Nigeria

  • Olusola A. Adejumoa
  • Olusoji J. Daniel
  • Andrew F. Otesanya
  • Adebukola A. Adegbola
  • Temitope Femi-Adebayo
  • Abimbola Bowale
  • Sunday Adesola
  • Olugbenga O. Kuku
  • Kehinde O. Otemuyiwa
  • Shafaatu N. Oladega
  • Eze O. Johnson
  • Ayodeji A. Falana
  • Olusola Dawodu
  • Henry Owuna
  • Ganiyat Osoba
  • Adetokunbo Dacosta

Abstract

Background: This study assessed factors associated with TB/HIV co-infection among TB patients managed in a secondary health facility in Lagos Nigeria.
Materials and Methods: A retrospective review of treatment cards of patients seen at a secondary referral hospital between January 1 2014 and December 31 2014 was conducted. Treatment outcomes and factors associated with TB/HIV co-infection were assessed.
Results: Of the 334 records of patients reviewed, the proportion of patients with TB/HIV co-infection was 21.6%. The odds of having TB/HIV co-infection was 2.7 times higher among patients above 40 years than patients less than 25 years (AOR 2.7 95% CI 1.1 – 6.5, p =0.030). In addition, the odds of having TB/HIV co-infection was 3.3 higher among extrapulmonary TB cases (AOR 3.3; 95% CI 1.2 – 9.5; p = 0.026) and 2.1 times higher among retreated patients (AOR 2.1; 95% CI 1.1 – 3.9; p = 0.017) than pulmonary TB and new patients respectively. The chance of having TB/HIV co-infection was 2.7-fold more in patients with poor treatment outcomes than patients with treatment success (AOR 2.7; 95%CI 1.3 – 5.4; p =0.006).
Conclusion: TB/HIV co-infection rate was high in the study area. There is need to put measures in place to improve treatment outcomes of TB/HIV co-infected patients.

Key Words: TB, HIV, co-infection, Nigeria

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eISSN: 2006-0165