Antidiabetic Activity Of Gladiolus psittascinus In Alloxan Induced Diabetic Rats

  • F-J Adediwura
  • A Kio
Keywords: <i>Gladiolus psittascinus</i>, hypoglycaemic activity, diabetes mellitus.


The methanol extract of Gladiolus psittascinus bulb was evaluated for its antidiabetic activities in alloxan-induced diabetic rats. Blood glucose levels of the glucose loaded and alloxaninduced diabetic rats were estimated over 180 minutes using the O-toluidine and glucose-oxidase methods. The methanol extract at 1g/kg dose exhibited 16.2% decrease in blood glucose level in the glucose loaded rats and a peak effect of 78.9% in the alloxan-induced diabetic rats. The extract exhibited significant blood glucose lowering effects in the oral glucose tolerance test and type 2 diabetic rats. This study shows a possible beneficial effect of Gladiolus psittascinus in the management of non-insulin dependent diabetes (NIDDM).

Keywords: Gladiolus psittascinus, hypoglycaemic activity, diabetes mellitus.

Afr. Jnl of Trad Comp Alt medicine Vol. 5 (2) 2008: pp. 154-157

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eISSN: 0189-6016