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African Journal of Traditional, Complementary and Alternative Medicines

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Antiulcerogenic activity of ethanolic leaf extract of Lasianthera africana

J Okokon, B Antia, E Umoh

Abstract


The effect of ethanolic leaf extract of Lasianthera africana on experimentally induced ulcer was studied in rats. The extract (1000 – 3000mg/kg) inhibited ethanol-induced, indomethacin – induced and reserpine –induced ulcer models in a dose dependent fashion. The various degrees of inhibitions were statistically significant (p<0.01). The effect of the extract was comparable to that of the standard drugs used. Thus, Lasianthera africana extract demonstrated a good antiulcer activity which supports the antiulcer effect of this plant in traditional medicine.

Key words: Lasianthera africana, antiulcer, vegetable




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