A study on the inhibitory effect of matrine on gastric cancer SGC-7901 cells

  • S Song
  • S Zhu
  • Z Zhang
  • Z Mo
  • Q Ke
  • Z Luo
Keywords: Matrine, SGC-7901, MTT assay

Abstract

The objective of this paper was to investigate the antitumour mechanism of action of matrine by studying its inhibitory effect on gastric cancer SGC-7901 cells. SGC-7901 cells were chosen, and cell-killing capacity of matrine on gastric cancer SGC-7901 cells was determined using MTT assay and single PI staining assay. The results showed that matrine had an inhibitory effect on gastric cancer SGC-7901 cells, which was somewhat dose-dependent. The study concluded that matrine has a significant in-vitro inhibitory effect on SGC-7901 tumour cells, influences cell cycle of SGC-7901 cells, and induces their apoptosis.

Key words: Matrine; SGC-7901; MTT assay

Published
2013-10-14
Section
Articles

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eISSN: 0189-6016