Antibacterial and healing potentials of CHARMIL® as a surgical wound dressing agent in goats
The antibacterial prophylaxis and wound healing potentials of Charmil® were assessed using rumenotomy procedure in twelve West African Dwarf Goats (WADG) .Following their acclimatization, the animals were divided into three groups of four animals each, with normal saline serving as negative control treatment whereas the (Tetrasol®) group served as positive control. . The incision wounds were swabbed for bacterial culture immediately after the closure of the surgical site on post surgical day (P. sd.) 0, and P.sds 3,7,10, and 14. The daily clinical records which include the assessment of wound healing process as wetness, dryness, crust formation and scar tissue formation (S.T.F.) were obtained during the same period. The rate of wound healing in the three groups revealed that by the 14th day P.S. all the wounds treated with both Charmil® and oxytetracycline spray healed completely while those of the normal saline treated group healed at a much slower rate. Though Tetrasol® exhibited higher antimicrobial activity than Charmil®, there is no significant difference (P>0.05) between the two agents. In this study therefore Charmil® demonstrated very high antimicrobial and healing potentials in comparison to that of Oxytetracycline spray. The study shows that though Charmil® could be used as a sole prophylactic wound dressing agent, there is a strong need for the manufacturers of the product to make public the active constituents of the product to encourage its' wider application in Veterinary practice.
Keywords: Antibacterial, wound Healing, charmil®, Surgical Dressing Agent, Goat.
> Agro-Science Vol. 6 (1) 2007: pp. 63-70