Extensive Epidermodysplasia Verruciformis in an HIV Infected Man: A Case Report

Abstract

Epidermodysplasia Verruciformis (EV) is a rare genodermatosis that may be hereditary or acquired, characterised by an abnormal predilection to infection by certain types of Human papilloma virus (HPV). The risk of acquired epidermodysplasia verruciformis increases with immunosuppression, as seen in HIV infected individuals, organ transplant recipients, patients with lymphoma, lupus patients and those on certain biologic therapy. There is an increased susceptibility to non-melanoma skin cancer, especially squamous cell carcinoma. There is no definitive treatment for epidermodysplasia verruciformis, therefore, early diagnosis, skin surveillance for malignancy and adequate sun protection is very pertinent. This is a case report of epidermodysplasia verruciformis is an HIV infected individual.