A new route to [1,2,4]triazolo[4,3-c][1,3,5,2]triazaphosphinine-5-oxides: reactivity of N-alkyl/aryl-n'-(4h-1,2,4-triazol-3-yl) amidines with N,N-dimethylphosphoramic dichloride

Abstract

A series of novel [1,2,4]triazolo[4,3-c][1,3,5,2]triazaphosphinine-5-oxidederivatives 2a-h were synthesized by a reaction of N-alkyl/aryl-N'-(4H-1,2,4-triazol-3-yl) amidines with N,N-dimethylphosphoramic dichloride in the presence of triethylamine (TEA) in refluxing 1,4-dioxane. The structures of all the synthesized compounds have been established by NMR (¹H, ¹³C, ³¹P) and IR spectroscopy, as well as by elemental analysis and mass spectral analysis.

Bull. Chem. Soc. Ethiop. 2020, 34(1), 157-161.

DOI: https://dx.doi.org/10.4314/bcse.v34i1.15