Bulletin of the Chemical Society of Ethiopia

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Isolation and investigation of antimicrobial effect of 3,4,3'-tri-O-methylflavellagic acid and its glucoside from Anogeissus leocarpus

J.O. Adigun, J.O. Amupitan, D.R. Kelly


3,4,3'-Tri-O-methylflavellagic acid and its glucoside (reported for the first time) were isolated from Anogeissus leocarpus. These compounds were analysed by GC-MS, IR, 1D and 2D-NMR, and also as acetates. Antimicrobial effect of the glucoside on S. aureus, E. coli, Ps. aeruginosa and C. albicans show that it possesses growth inhibitory effect at various concentrations.

(Received March 22, 2000; revised October 25, 2000)

Bull. Chem. Soc. Ethiop. 2000, 14(2), 169-174
AJOL African Journals Online