Isolation and investigation of antimicrobial effect of 3,4,3'-tri-O-methylflavellagic acid and its glucoside from Anogeissus leocarpus

  • J.O. Adigun Department of Chemistry, Ahmadu Bello University, Zaria, Nigeria
  • J.O. Amupitan Department of Chemistry, Ahmadu Bello University, Zaria, Nigeria
  • D.R. Kelly Department of Chemistry, University of Wales, P.O. Box 912, Cardiff, CF1 3TB, Wales, U.K.

Abstract

3,4,3'-Tri-O-methylflavellagic acid and its glucoside (reported for the first time) were isolated from Anogeissus leocarpus. These compounds were analysed by GC-MS, IR, 1D and 2D-NMR, and also as acetates. Antimicrobial effect of the glucoside on S. aureus, E. coli, Ps. aeruginosa and C. albicans show that it possesses growth inhibitory effect at various concentrations.
(Received March 22, 2000; revised October 25, 2000)

Bull. Chem. Soc. Ethiop. 2000, 14(2), 169-174
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Articles

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