An investigation of the stem bark of Erythrophleum suaveolens (Guill. & Perr.) Brenan yielded the known amide norcassaide (1) and a new diterpenoid alkaloid named norerythrosuaveolide (2) which was characterized as 7β-hydroxy-7-deoxo-6-oxonorcassaide. The structures were established on the basis of one and two-dimensional 1H and 13C NMR spectral data. The compounds showed potent antimicrobial activities against bacteria and yeasts.
KEY WORDS: Erythrophleum suaveolens (Guill. & Perr.) Brenan, Norcassaide, Diterpenoid alkaloid, Norerythrosuaveolide, Antimicrobial activities, Bacteria, Yeasts
Bull. Chem. Soc. Ethiop. 2005, 19(2), 221-226.