THE MASS OF CELLULAR RETINOIC ACID BINDING PROTEIN I INVESTIGATED BY 13C DEPLETION AND MASS SPECTROMETRY

  • Lin Zhang College of Science, Guangdong Ocean University, Zhanjiang, 524088, China
  • Zeqing Song Department of Internal Medicine, Guangdong Medical College, Zhanjiang, 524001, China
  • Yanmei Wen College of Science, Guangdong Ocean University, Zhanjiang, 524088, China
Keywords: Molecular mass, Mass accuracy, Isotopic depletion, Monoisotopic

Abstract

The accuracy of mass spectrometry used to determine large molecular mass as proteins is often influenced by the isotopic compositions within a protein. Isotopic depletion is a powerful tool to resolve this problem. Using Fourier transform ion cyclotron resonance mass spectrometer, we investigated the 13C depleted cellular retinoic acid binding protein I, the measured mass accuracy is increased compared with the natural protein
KEY WORDS: Molecular mass, Mass accuracy, Isotopic depletion, Monoisotopic

Bull. Chem. Soc. Ethiop. 2009, 23(1), 101-103.
Published
2009-04-01
Section
Articles

Journal Identifiers


eISSN: 1726-801X
print ISSN: 1011-3924