Nauclefolinine: A new alkaloid from the roots of Nauclea latifolia

D. Ngnokam; J.F. Ayafor; J.D. Connolly; J.M. Nuzillard

doi:10.4314/bcse.v17i2.61669

D. Ngnokam Department of Chemistry, University of Dschang, Box 67 Dschang, Cameroon
J.F. Ayafor Department of Chemistry, University of Dschang, Box 67 Dschang, Cameroon
J.D. Connolly Department of Organic Chemistry, University of Glasgow, Glasgow G12 8QQ, Scotland
J.M. Nuzillard CNRS-UPRESA 6013, Laboratoire de Pharmacognosie CPCBAT-Bâtiment 18, Moulin de la Housse, B.P. 1039, 51097 Reims cedex 2, France

DOI: 10.4314/bcse.v17i2.61669

Keywords: Nauclea latifolia, Rubiaceae, Indole alkaloid, Triterpenic acids, Rotundic acid, Rhamnoquinovic acid

Abstract

A novel indole alkaloid, nauclefolinine (1) and five known triterpenic compounds, rotundic acid (2), a-L-rhamnoquinovic acid (3), 3-O-b-D-glucopyranosyl-b-sitosterol (4), squalene (5) and sitosterol-3-O-6’-stearoyl-b-D-glucopyranoside (6) have been isolated from the roots of Nauclea latifolia.

KEY WORDS: Nauclea latifolia, Rubiaceae, Indole alkaloid, Triterpenic acids, Rotundic acid, Rhamnoquinovic acid

Bull. Chem. Soc. Ethiop. 2003, 17(2), 173-176.

Nauclefolinine: A new alkaloid from the roots of Nauclea latifolia

Abstract

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