DABCO as a novel and efficient catalyst for the synthesis of 4(3H)-quinazolinone derivatives

  • Majid M. Heravi Department of Chemistry, School of Science, Azzahra University, Vanak, Tehran, Iran
  • Najme Javanmardi Department of Chemistry, School of Science, Azzahra University, Vanak, Tehran, Iran
  • Hossein A. Oskooie Department of Chemistry, School of Science, Azzahra University, Vanak, Tehran, Iran
  • Bita Baghernejad Department of Chemistry, School of Science, Azzahra University, Vanak, Tehran, Iran
DOI: 10.4314/bcse.v25i2.65909
Keywords: 4(3<i>H</i>)-Quinazolinone, DABCO (1, 4-diazabicyclo[2, 2, 2]octane), Trimethyl orthoformate, Anthranilic acid

Abstract

4(3H)-Quinazolinones were synthesized in high to excellent yields through the one-pot condensation of anthranilic acid, trimethyl orthoformate and primary amines in the presence of DABCO under solvent free conditions.

KEY WORDS: 4(3H)-Quinazolinone, DABCO (1,4-diazabicyclo[2,2,2]octane), Trimethyl orthoformate, Anthranilic acid

 

Bull. Chem. Soc. Ethiop. 2011, 25(2), 305-308.
Published
2011-05-02
Issue
Vol. 25 No. 2 (2011)
Section
Articles

Journal Identifiers


eISSN: 1726-801X
print ISSN: 1011-3924