DABCO as a novel and efficient catalyst for the synthesis of 4(3H)-quinazolinone derivatives
4(3H)-Quinazolinones were synthesized in high to excellent yields through the one-pot condensation of anthranilic acid, trimethyl orthoformate and primary amines in the presence of DABCO under solvent free conditions.
KEY WORDS: 4(3H)-Quinazolinone, DABCO (1,4-diazabicyclo[2,2,2]octane), Trimethyl orthoformate, Anthranilic acid
Bull. Chem. Soc. Ethiop. 2011, 25(2), 305-308.