Mesoporous molecular sieve MCM-41 catalyzed one-pot synthesis of 3,4-dihydro-2(1H)-pyrimidinones and –thiones under solvent-free conditions

Rahim Hekmatshoar; Maryam Heidari; Majid. M. Heravi; Bita Baghernejad

doi:10.4314/bcse.v25i2.65910

Rahim Hekmatshoar Department of Chemistry, School of Science, Alzahra University, Vanak, Tehran, Iran
Maryam Heidari Department of Chemistry, School of Science, Alzahra University, Vanak, Tehran, Iran
Majid. M. Heravi Department of Chemistry, School of Science, Alzahra University, Vanak, Tehran, Iran
Bita Baghernejad Department of Chemistry, School of Science, Alzahra University, Vanak, Tehran, Iran

DOI: 10.4314/bcse.v25i2.65910

Keywords: Biginelli reaction, Dihydropyrimidinones, MCM-41, One-pot, Reusable

Abstract

An efficient synthesis of 3,4-dihydro-2(1H)-pyrimidinones and -thiones using MCM-41 as the catalyst from an aldehyde, β-keto ester, and urea or thiourea under solvent-free conditions is described.

KEY WORDS: Biginelli reaction, Dihydropyrimidinones, MCM-41, One-pot, Reusable

Bull. Chem. Soc. Ethiop. 2011, 25(2), 309-313.

Mesoporous molecular sieve MCM-41 catalyzed one-pot synthesis of 3,4-dihydro-2(1H)-pyrimidinones and –thiones under solvent-free conditions

Abstract

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