Cameroon Journal of Experimental Biology

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Phytoconstituents and preliminary antiradical property evaluation of Baillonella toxisperma (Sapotaceae)

Kevine J.J. Dongmo, Romuald T. Fouedjou, Billy T. Tchegnitegni, Beaudelaire K. Ponou, Rémy B. Teponno, Kristina J. Siems, Matthias F. Melzig, Léon A. Tapondjou


From the EtOAc fraction of the methanol extract of the stem barks of Baillonella toxisperma (Sapotaceae), eight compounds were isolated using column chromatography techniques. Their structures were established on the basis of 1D and 2D-NMR data and comparison with data published in the literature. The MeOH extract, n-BuOH and EtOAc fractions together with some pure compounds (4, 5, 7, 8) were screened for their radical scavenging activity using the2,2-diphenyl-1- picryl-hydrazyl-hydrate (DPPH) free radical in order to get preliminary information about the antiradical capacities of this plant.

Keywords: Baillonella toxisperma;Sapotaceae; DPPH; Antiradical activity

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