Investigation of metabolic encephalopathy

  • GF van der Watt


Encephalopathy may be a presenting sign in a wide range of medical conditions. This review focuses only on the diagnosis and initial management of those inherited metabolic diseases (IMDs) prevalent in South Africa that may present with encephalopathy in childhood. Metabolic encephalopathy is a medical emergency, and appropriate empirical intervention can often improve outcome, provided a timely working diagnosis is made based on clinical suspicion and targeted laboratory investigations.

CME January 2013 Vol. 31 No. 1

Author Biography

GF van der Watt
Division of Chemical Pathology, Groote Schuur Hospital and Red Cross War Memorial Children’s Hospital, University of Cape Town and National Health Laboratory Service

Journal Identifiers

eISSN: 2078-5143
print ISSN: 0256-2170