Pattern of distribution of patients presenting with osteogenesis imperfecta at AIC cure Children's International Hospital, Kijabe

  • GC Mwangi
  • JT Macharia


Background: Osteogenesis imperfecta is one of the common diseases encountered at AIC CURE Children’s International Hospital (Cure Hospital Kenya).  Osteogenesis imperfecta is a rare condition constituting 2% of all cases seen at the hospital. The Cure Hospital runs 15 clinics throughout Kenya, in which osteogenesis imperfecta is frequently encountered .
Objective: The study was carried out to determine the tribal and geographical distribution of patients with osteogenesis imperfecta in Kenya.
Design: This was a 14 year retrospective review study.
Setting: Cure Hospital, Kenya.
Materials and methods: The medical charts of all patients admitted with  Osteogenesis Imperfecta (OI) over a period of 14 years [2000 to 2014] were reviewed.
Results: A total of 80 patients with osteogenesis imperfecta were seen. Fifty seven point five percent of the patients with OI were males and 42.5% were females. Thirty seven point five percent were of Kamba origin while 28.8% were from the Kikuyu tribe. Majority of these patients came from Eastern region of Kenya with 26.25% coming from Machakos and 30 out of the total of 80 patients were from Kamba tribe.
Conclusions: Most of these patients come from Eastern region of Kenya. Majority of patients with OI were of Kamba origin followed by the Kikuyu tribe. A larger epidemiological study needs to be carried out to more conclusively determine the relative prevalence and genetic patterns of osteogenesis imperfecta in Kenya.

Journal Identifiers

eISSN: 1994-1072
print ISSN: 1994-1072