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The role of prostaglandins in livestock production

B Okon
L.A. Ibom
A.E. Bassey
F.I. Okon


Prostaglandins belong to the family of lipid. Soluble unsaturated hydroxyl acid containing twenty carbon (c) atoms and based on the prostanoic acid skeleton. There are two main types of Prostaglandins (PGs), the E and F series each having 3 members E1, E2, E3 and F1σ, F2σ, F3σ. The other PGs are known as secondary PGs and are products of enzymic or chemical dehydrations of PGEs e.g PG+2, PGA2, PGD2 and PGB. Prostaglandins are probably the most important regulators of female productive functions (ovulation, uterine receptivity, Implantation and parturition) and associated with pathologies (pain, fever, and inflammation), apart from sex steroids. Prostaglandins are not stored in tissues but are synthesized and released in response to a given stimulus. Prostaglandins are produced by all nucleated cells of the body and act locally in a paracrine (locally active) or autocrine (acting on the same cell from which it is in a synthesized) fashion. Prostaglandins are therefore regarded as essential mediators of female reproductive processes, hence, this paper seeks to review the role of Prostaglandins which is exploited in livestock production especially oestrus synchronization and induced parturition.

KEYWORDS: Prostaglandins, Production, Role, Livestock