The effect of the sub-lethal dose 3.0mg/l (of dechlorinated water) of Piper guineense on the histology of Liver and Kidney of Oreochromis niloticus exposed for 21 days in a static bioassay revealed some pathological changes in liver and kidney of the fish. These include vacuolation, liver cord disarray/necrosis and the distortion of the organized cellular pattern. These findings revealed the destructive property of P. guineense as an ichthyotoxic plant. The effects of ichthyotoxic plants vis-à-vis other fish poisons are discussed in the wild and natural environment.
(Global Journal of Pure and Applied Sciences: 2002 8(2): 193-196)