Management of TB/HIV co-infection: the state of the evidence

  • Kwasi Torpey Department of Population, Family and Reproductive Health, University of Ghana School of Public Health
  • Adwoa Agyei-Nkansah Department of Medicine and Therapeutics, University of Ghana Medical School
  • Lily Ogyiri Department of Population, Family and Reproductive Health, University of Ghana School of Public Health
  • Audrey Forson Department of Medicine and Therapeutics, University of Ghana Medical School
  • Margaret Lartey Department of Medicine and Therapeutics, University of Ghana Medical School
  • William Ampofo Department of Virology, University of Ghana Noguchi Memorial Institute of Medical Research
  • Joseph Akamah Department of Medicine and Therapeutics, University of Ghana Medical School
  • Peter Puplampu Department of Medicine and Therapeutics, University of Ghana Medical School
Keywords: Tuberculosis; management; HIV; MDR TB; Ghana

Abstract

Tuberculosis (TB) and HIV are strongly linked. There is a 19 times increased risk of developing active TB in people living with HIV than in HIV-negative people with Sub-Saharan Africa being the hardest hit region. According to the WHO, 1.3 million people died from TB, and an additional 300,000 TB-related deaths among people living with HIV. Although some progress has been made in reducing TB-related deaths among people living with HIV due to the evolution of diagnostics, treatment and antiretroviral HIV treatment, multi drug resistant TB is becoming a source of worry. Though significant progress has been made at the national level, understanding the state of the evidence and the challenges will better inform the national response of the opportunities for improved patient outcomes.
Keywords: Tuberculosis, management, HIV, MDR TB, Ghana
Funding: None

Published
2020-09-30
Section
Articles

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print ISSN: 0016-9560