Antibiotic sensitivity pattern of urinary tract pathogens in Port – Harcourt, Nigeria

  • JC Uwaezuoke Imo State University P.M.B. 2000, Owerri, Nigeria
  • JN Ogbulie Federal University of Technology, Owerri, Nigeria


The prevalence and sensitivity pattern of urinary pathogens from 1240 patients in Port-harcourt, Nigeria was investigated. The predominant pathogens cultured was E. coli which accounted for 76.6% of the infections. Klebsiella spp was responsible for 8.1% of cases while the rest were accounted for by Proteus spp (4.8%), coagulase-negative staphylococci (3.2%), Pseudomonas spp (2.4%), Enterobacter spp. (2.4%), Staphylococcus aureus (1.6%) and Citrobacter species (0.8%). The majority of the isolates were resistant to tetracycline (75.8%), ampicillin (71.0%) and cotrimoxazole (65.3%) but exhibited good sensitivity to nitrofurantoin (88.7%), gentamicin (85.5%) and nalidixic acid (76.6%). It is recommended that a periodic reassessment of the sensitivity pattern of urinary pathogens be carried out to serve as a guide for antibiotic therapy of UTIs in a particular environment since these organisms exhibited resistance to first-line drugs used for UTI infections.

Journal of Applied Sciences and Environmental Management Vol. 10(3) 2006: 103-107

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eISSN: 2659-1502
print ISSN: 1119-8362