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The aim of this study is to determine the prevalence and pattern of degenerations in leiomyomas. We sought to relate these degenerations with clinical features. It is a retrospective study of histological features of specimens of leiomyomas obtained at the myomectomy, hysterectomy and polypectomy. Results showed that 88.89% had degenerations. Hyaline degeneration was the commonest accounting for 89.71% of all degenerations followed by cystic degeneration (15.44%), calcification (8.82%) and red degeneration which was the least common (5.15%). The clinical features seen in our series cannot be reliably matched with any particular pattern of degeneration. However, lower abdominal pain seems to be a constant feature in red degeneration of fibroids. There is a high prevalence of degenerative changes in leiomyomas of Nigerian Igbo women.
Key words: Leiomyoma, degeneration, pattern