PROMOTING ACCESS TO AFRICAN RESEARCH

Journal of Medical Laboratory Science

Log in or Register to get access to full text downloads.

Remember me or Register



DOWNLOAD FULL TEXT Open Access  DOWNLOAD FULL TEXT Subscription or Fee Access

Effect of Cola acuminate on Blood Glucose and Glycosylated Haemoglobin in Wistar Rats

JC Onyeanusi, VPO Ikpe

Abstract


The levels of blood glucose and glycosylated haemoglobin (GHB) were studied in 42 Wistar rats divided into three groups; controls, group A and group B. Control rats consumed only feeds, group A consumed 0.04g of Cola acuminate, while group B consumed 0.08g of Cola acuminate mixed with their feeds daily for six consecutive weeks. Blood samples were collected weekly for analysis. Baseline values increased by 22% for blood glucose in group A and by 29% in group B. GHB also increased relatively and correlated well with blood glucose in group A (r = 0.70; P < 0.05) and in group B (r = 0.73; P < 0.05). Regular kolanut consumption elevates blood glucose and GHB levels, while withdrawal returns these parameters progressively to pre-kolanut consumption levels.
Key words: kolanut diet, rat blood glucose, glycosylated haemoglobin
Journal of Medical Laboratory Science Vol.13(1) 2004: 41 - 44



http://dx.doi.org/10.4314/jmls.v13i1.35296
AJOL African Journals Online