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Journal of Pharmacy & Bioresources

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Antifungal evaluation and phytochemical screening of methanolic extract and fractions of Boswellia dalzielii stem bark

Yves S. Kafuti, Stephen O. Ojerinde, Opeyemi Balogun, Taiwo E. Alemika, Kalulu M. Taba, Pius T. Mpiana, Nice M. Kindombe

Abstract


The objective of the study was to further examine the medicinal value of Boswellia dalzielii plant by evaluating the antifungal activity and carrying out phytochemical screening of methanolic extract, hexane, ethyl acetate, aqueous fractions and the sub-fractions of the stem bark of the plant. Standard methods were used for the evaluation of phytochemical screening. Seeded plate method was used for the antifungal test procedures. The phytochemical screening of the stem bark of B. dalzielii indicated the presence of tannins, saponins, flavonoids, steroids, carbohydrate. The methanolic extract, fractions and sub-fractions showed activity against Candida albicans; ethyl acetate and aqueous fractions showed activity against Penicillium notatum, while the methanolic extract, fractions and sub-fractions had no activity against Aspergillus niger. These results underscore the importance of Boswellia dalzielii as a potential source of antifungal agents.

Keywords: Antifungal; Boswellia dalzielii; Phytochemical; Stem bark




http://dx.doi.org/10.4314/jpb.v14i1.8
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