Article Sidebar
Article Details
Issue
Section
Articles
Copyright of articles published shall reside exclusively with the Faculty of Pharmaceutical Sciences, University of Jos.
DECLARATION & COPYRIGHT TRANSFER
I/We the undersigned author(s) of article entitled
…………………………………………………………………………………………………………………
…………………………………………………………………………………………………………………
Declare as follows:
- The manuscript submitted to Journal of Pharmacy & Bioresources is original and has not been and will be published, whole or in part, in print or electronic format, in any other journal. It is also not being currently considered for publication in any journal.
- The submitted manuscript is a joint decision of all the coauthors.
- Each author has participated sufficiently in the work to warrant his or her inclusion in the list of authors. To this end, each author takes responsibility for appropriate portions of the manuscript.
- Authors have obtained necessary approval to carry out the experiments on animals and human subjects. Approval certificates will be furnished, if required by publishers or editors of the journal.
- Authors do not have any conflict of interest (financial or otherwise) other than those declared.
- If the manuscript is accepted for publication, the authors transfer and assign copyright of the article referenced above to Journal of Pharmacy and Bioresources.
Name & Signature of authors
1. 2.
- 4.
- 6.
- 8.
Corresponding authors name address, affiliation and email:
Main Article Content
Isolation and characterisation of cupressuflavone from the leaves of <i>Lophira lanceolata</i>
Abstract
The leaf of Lophira lanceolata (Ochnaceae) is used by traditional medicine practitioners in Africa and other parts of the world to treat dysentery. Preliminary phytochemical examination of the extracts of the leaves of Lophira lanceolata indicated the presence of flavonoids, anthraquinones, cardiac glycosides, tannins, saponins and free reducing sugar while alkaloids are absent. The acetone extract of the plant.s leaves was subjected to extensive column and thin-layer chromatography on silica. This afforded a compound characterized as cupressuflavone, a biflavonoid. The structure was elucidated using spectroscopic techniques, - UV, IR, NMR (2-D) and MS
(Electrosspray Ionisation . ESI). Spectroscopic data obtained are consistent with literature values for cupressuflavone. Preparation of methylated and acetylated derivatives was carried out, for confirmation.
(Electrosspray Ionisation . ESI). Spectroscopic data obtained are consistent with literature values for cupressuflavone. Preparation of methylated and acetylated derivatives was carried out, for confirmation.
