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Journal Tunisien d'ORL et de Chirurgie Cervico-Faciale

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Dosage plasmatique et globulaire du magnesium dans l’exploration de la rhinite allergique

G Ondzotto, M Diatewa, T Fouemina, J Koutihou, F Bissiko

Abstract


Objectives: The allergic rhinitis represents a real public health problem. The goal of this survey is to value the interest of the dosage
plasmatical and globular of magnesium in the diagnosis of the allergic rhinitis.
Materials and methods : Analytic and prospective survey of 80 files, on one period of 4 years and 5 months (from January 2004 to may
2008), including the patients presenting an allergic rhinitis, matched to 80 witnesses for the sex and age. The blood withdrawals have been done in any case in the same conditions, the morning on an empty stomach. The dosage of magnesium has been achieved thanks to an atomic absorption spectrophotometer (SCREEN MASTER) according to the method colorimetrical. The parameters of survey were the next one: epidemiological features and clinical aspects of the allergic rhinitis; middle rates of magnesium plasmatical and globular, the pathological
doorsteps observed among the witness; values of magnesium plasmatical and globular lowered and pathological observed at the patients.
Results : Our set included 43.75% of men and 56.25% of women aged of 6-45 years (average of age: 27 years). The slices of 16-35
years represent 76.25% of the cases. The personal antecedents (20%) and familiar (60%) atopy was recovered. The length of the rhinitis
was of 1-20 years (average: 9 years). The classic triad made of aqueous rhinorrea (72%), sneezes in salvos (60.8%) and nasal obstruction
(58.2%); as well as the pituitary paleness (56.2%), the pruritus (50.25%) were the dominant clinical elements. The illness evolved
under the obstinate shape in the totality of the cases.
The witnesses presented: a middle rate of magnesium plasmatical of 21.1 mg/l ± 0.98 and a pathological doorstep of 15.7 mg/l < 21.1
mg/l < 26.5 mg/l; a middle rate of globular magnesium of 57.05 mg/l ± 2.42 and a pathological doorstep of 44.79 mg/l < 57.05 mg/l < 69.31 mg/l. The sick topics had in: 50% of the cases a lowered magnesium plasmatical; 68.75% of the cases lowered globular magnesium; 37.5%
of the cases a magnesium plasmatical and globular lowered; 23.75% of the cases pathological globular magnesium; 5% of the cases a
magnesium pathological plasmatic; 3.75% of the cases a magnesium plasmatical and globular pathological.
Conclusion: The decrease of magnesium in blood concerns the globular fraction more than plasmatic. The dosage of the magnesium
is an element of decorate-clinic orientation in the diagnosis of the allergic rhinitis. The magnesotherapy presents a certain interest in the
hold in charge of this pathology.



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