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Carcinome adenoide kystique sous-glottique


E Gassab
N Krifa
K Harrathi
A Moussa
J Koubaa
A Gassab

Abstract

Introduction: Laryngeal adenoid cystic carcinoma (ACC) is unusual. It accounts for 0.25% of all malignant tumors in the larynx, and only about 120 cases have been reported in the literature until now.
Purpose: We report a case of subglottic ACC and examine the clinical, diagnostic, histological and therapeutic features and the outcome of this tumor in this location.
Case report: A 75-year-old man, presented with a laryngeal dyspnea. The computed tomography of the larynx showed a posterior subglottic tumor. The panendoscopy revealed a large nonulcerated submucosal tumor in the posterior wall of the subglottic area. Biopsies made the diagnosis of laryngeal ACC. The patient had total laryngectomy with total thyroidectomy
and bilateral lateral neck dissection. Histological examination didn't find neck metastases. The surgery was followed by a postoperative radiotherapy. There were no local recurrence or distant metastases during one year and half of follow-up.
Conclusions: ACC shows a very slow growth pattern. Its diagnosis is often delayed and its treatment is based on surgery and postoperative radiotherapy. This tumor is characterized by the occurrence of local recurrence and distant metastases often several years after treatment of the primary tumor.

Keywords: adenoid cystic carcinoma, subglottic, surgery, postoperative radiotherapy, survival.


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eISSN: 1737-7803