Journal Tunisien d'ORL et de Chirurgie Cervico-Faciale

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Lymphomes malins non-hodgkiniens primitifs des amygdales palatines

I Harga, S Zribi, A Bouzayani, FBH Younes, K Khammassi, M Benamor, OB Gamra, CH M'barek, A El khedim


Introduction: The most predominant localization for extranodal  non-hodgkinien lymphoma (NHL) in the head and neck region is the tonsil. The vast majority of NHL at this site is B-cell lymphomas.
Materials and methods: The authors presented three cases of primary Non Hodgkin's Lymphoma of the tonsil, treated between 1995 and 2007
Results: we report the cases of three men aged respectively 15, 42 and 72 years. They complained of a persistent odynophagia during three months ago. Clinical examination detected unilateral enlarged tonsil with ulcerated surface. All of them have bilateral tonsillectomy. The histopathologic examination concluded at a NHL with a B phenotype. The treatment consisted on chemotherapy for two patients and on radio and  chemotherapy for the third patient. We have noted one death for our three patients.
Conclusion: Primary NHL of the tonsil is rare. An advanced diagnosis is often difficult. Both histopathologic identification of the tumor and evaluation of the patient are essentiel for the therapeutic decision. Prognostic depends on the stage of the lymphoma.
Keywords: Non Hodgkin lymphoma, Oral cavity, Radiotherapy, Chemotherapy, antineoplastic agent, malignant hemopathy, Oral cavity disease.

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