Nutritive-element interactions: a review

  • J. B. ADEKALU Department of Biochemistry, Faculty of Science, Lagos State University, Badagry Express Way, Ojo, P.m.b 1087, Apapa, Lagos State.


There is ample evidence that competitive mineral interactions take place in organism between nutritive elements as well as non-nutritive elements. These interactions could potentially occur within a food or food system at the site of absorption yet metabolically active site. The competition may be between two nutritive elements, a nutritive and non-nutritive element or between two toxic elements. Thus, elemental interactions may be deleterious or potentially advantageous, depending on the element and/or interactions in view. Elemental interactions that are of nutritional or pharmacological significance in mammals include the Zn – Cu antagonism, the Fe – Cu effects, Fe – Zn effect, Na – K interaction, Mg2+ – Ca2+ effect, and Mg – Zn interaction. The major competitive mineral interactions are discussed in detail, wherever possible, with the clinical disorders that might be produced as a consequence of the interaction in question.

Key Words:Interaction, trace elements, major elements, Nutritive elements.

Nig. Jnl Health & Biomedical Sciences Vol.2(1) 2003: 35-39

Journal Identifiers

eISSN: 1595-8272