Effects of 2.45 GHz Radiofrequency Radiation Exposures on Normal and Sickle Erythrocytes

  • MA Aweda Department of Radiation Biology and Radiotherapy, College of Medicine of the University of Lagos/Lagos University Teaching Hospital, Idi-araba, P. M. B. 12003, Lagos, Nigeria
  • SO Gbenebitse Department of Physiology, College of Medicine of the University of Lagos/Lagos University Teaching Hospital, Idi-araba, P. M. B. 12003, Lagos, Nigeria
  • MO Kehinde Department of Medicine, College of Medicine of the University of Lagos/Lagos University Teaching Hospital, Idi-araba, P. M. B. 12003, Lagos, Nigeria
Keywords: Radiofrequency radiation, Sickle cells, Non-sickle cells, Osmotic fragility

Abstract

Twenty subjects were used for the study, ten adult sickle cell and ten adult non-sickle cell patients. Blood samples were collected for analysis before and after being irradiated with a 2.45 GHz radiofrequency source. The osmotic fragility of the red blood cells, the packed cell volume and percentage haemolysis for irreversibly sickled cells and non-sickle cells were determined, and the results compared.

It was discovered that osmotic fragility of sickle cell subjects was much higher than that of non-sickle cell subjects. The mean corpuscular fragility of sickle cells observed was less than that of non–sickle cells. The value at Complete Lyses for non-sickle cells before irradiation HbAAb was 0.22 ± 0.01% and after HbAAa, it was 0.23 ± 0.02% with a p-value < 0.05. In the sickle cells samples before HbSSb and after HbSSa, the values were 0.12 ± 0.01% and 0.42 ± 0.01% respectively with p-value < 0.01.

The PCV values for the HbAAb sample ranged from 37.50 to 55.49% with a mean (± SEM) of 44.93 ± 0.90%. The range for the HbAAa was from 26.02 to 34.12% giving a mean of 30.12 ± 0.20% (with p < 0.01). The values for the HbSSb sample ranged between 20.00 and 34.00% giving a mean of 26.53 ± 1.20% while for the HbSSa, the range was 1.00 to 6.06%, giving a mean value of 5.06 ± 1.00% (p < 0.01). The results obtained demonstrate that exposures to 2.45 GHz radiofrequency radiation have much harmful effects on sickle cell and have no significant effect on non-sickle cell carriers. The percentage of haemolysis remains persistently high after exposure of sickled cells while that of non-sickle cells showed little variations compared with control.

KEY WORDS: Radiofrequency radiation, Sickle cells, Non-sickle cells, Osmotic fragility.

Nig. Jnl Health & Biomed. Sciences Vol.3(1) 2004: 56-59
Published
2004-04-23
Section
Articles

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eISSN: 1595-8272