Nigerian Journal of Health and Biomedical Sciences

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Effects of 2.45 GHz Radiofrequency Radiation Exposures on Normal and Sickle Erythrocytes

MA Aweda, SO Gbenebitse, MO Kehinde


Twenty subjects were used for the study, ten adult sickle cell and ten adult non-sickle cell patients. Blood samples were collected for analysis before and after being irradiated with a 2.45 GHz radiofrequency source. The osmotic fragility of the red blood cells, the packed cell volume and percentage haemolysis for irreversibly sickled cells and non-sickle cells were determined, and the results compared.

It was discovered that osmotic fragility of sickle cell subjects was much higher than that of non-sickle cell subjects. The mean corpuscular fragility of sickle cells observed was less than that of non–sickle cells. The value at Complete Lyses for non-sickle cells before irradiation HbAAb was 0.22 ± 0.01% and after HbAAa, it was 0.23 ± 0.02% with a p-value < 0.05. In the sickle cells samples before HbSSb and after HbSSa, the values were 0.12 ± 0.01% and 0.42 ± 0.01% respectively with p-value < 0.01.

The PCV values for the HbAAb sample ranged from 37.50 to 55.49% with a mean (± SEM) of 44.93 ± 0.90%. The range for the HbAAa was from 26.02 to 34.12% giving a mean of 30.12 ± 0.20% (with p < 0.01). The values for the HbSSb sample ranged between 20.00 and 34.00% giving a mean of 26.53 ± 1.20% while for the HbSSa, the range was 1.00 to 6.06%, giving a mean value of 5.06 ± 1.00% (p < 0.01). The results obtained demonstrate that exposures to 2.45 GHz radiofrequency radiation have much harmful effects on sickle cell and have no significant effect on non-sickle cell carriers. The percentage of haemolysis remains persistently high after exposure of sickled cells while that of non-sickle cells showed little variations compared with control.

KEY WORDS: Radiofrequency radiation, Sickle cells, Non-sickle cells, Osmotic fragility.

Nig. Jnl Health & Biomed. Sciences Vol.3(1) 2004: 56-59
AJOL African Journals Online