ECOTOXICITY AND SOME PHARMACOPOEIAL STANDARDS OF THE MOLLUSCICIDES: TETRAPLEURA TETRAPTERA

  • CO Adewunmi Drug Research and Production Unit, Faculty of Pharmacy, Obafemi Awolowo University, Ile-Ife, Nigeria
  • JM Agbedahunsi Drug Research and Production Unit, Faculty of Pharmacy, Obafemi Awolowo University, Ile-Ife, Nigeria
  • AA Elujoba Drug Research and Production Unit, Faculty of Pharmacy, Obafemi Awolowo University, Ile-Ife, Nigeria
  • JAO Ojewole Department of Pharmacology, Faculty of Health Sciences, University of Durban-Westville, Private Bag X54001 Durban 4000, South Africa.
Keywords: Terapleura tetraptera, molluscicide, pharmacopieal values, ecotoxicity

Abstract

Total, acid-insoluble, water-soluble ash, as well as water-soluble extractive values of Tetraleura tetraptera has been examined. The values were highest in the savanna zone samples. Values of the numerical standards were found to vary as follows: Savanna transitional forest (rainforest frontier) >rainforest. The rank orderof the water-soluble extractive according to location was found to be: Ilora (savanna, 14.64+0.05%), Omuo-Oke (derived savanna, 4,64+0.05%)> Owena (rainforest 5.72+0.15%). The alcohol-soluble extractive was highest (6.63+0.20%) at derived savanna zone (Omuo-Oke). The rank order of the alcoholic extractive was also found to be: Omuo-Oke (savanna, 6.63+0.20%)> Ilugun/Olokemeji (derived savanna 6.46+0.12%)>Abata Egba (rainforest, 4.45+0.06%). T. tetraptera was found to be less toxic to Thermocyclops oblongatus; earthworms and Paramecium spp. than Biomphalaria glabrata snails, but more toxic to cyprids, Clarias spp. and Epiplatys spp.

Key Words: Terapleura tetraptera, molluscicide; pharmacopieal values, ecotoxicity.

Nig. J. Nat Prod. And Med. Vol.5 2001: 8-12
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