Hypoglycemic Effect Of Alcoholic Extract Of Various Species Of Passiflora On Alloxan Induced Diabetes Mellitus In Albino Rats

  • SP Dhanabal Department of Pharmacognosy and Pharmacology, JSS College of Pharmacy, Rocklands, Ootacamund - 643 001,Tamilnadu, India
  • Jerald E Edwin Department of Pharmacognosy and Pharmacology, JSS College of Pharmacy, Rocklands, Ootacamund - 643 001,Tamilnadu, India
  • EP Kumar Department of Pharmacognosy and Pharmacology, JSS College of Pharmacy, Rocklands, Ootacamund - 643 001,Tamilnadu, India
  • B Suresh Department of Pharmacognosy and Pharmacology, JSS College of Pharmacy, Rocklands, Ootacamund - 643 001,Tamilnadu, India
Keywords: <i>Passiflora species</i>, Passifloracea, <i>Diabetes</i> Glucose, Antihyperglycaemic, Alloxan

Abstract

Oral administration of alcoholic extracts of leaves of Passiflora edulis, P. mollisima and P. quadrangularis used in Indian folklore medicine for the treatment of diabetes mellitus produced a gradual but significant reduction in blood glucose in alloxan treated hyperglycaemic rats at 100 and 200 mg/kg body weight over a period of eight days compared to the phenformin treated controls. It was concluded that the leaves of Passiflora species may have a beneficial effect in diabetes mellitus.
Key words: Passiflora species; Passifloracea, Diabetes Glucose; Antihyperglycaemic; Alloxan
Nig. J. Nat. Prod. and Med. Vol.8 2004: 19-21
Published
2005-06-23
Section
Articles

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eISSN: 1118-6267