8-(2-Methylbutanoyl)-3, 10 Epoxy-3, 8-Dihydroxyl-4, 11 (13)- Germacradien-12, 6-Olide A New Sesquiterpene Lactone From Tithonia diversifolia

  • TO Elufioye Drug Research and Production Unit, Faculty of Pharmacy, Obafemi Awolowo University, Ile Ife Nigeria
  • JM Agbedahunsi Drug Research and Production Unit, Faculty of Pharmacy, Obafemi Awolowo University, Ile Ife Nigeria
  • SA Adesanya Department of Pharmacognosy, Faculty of Pharmacy Obafemi Awolowo University, Ile ife, Nigeri
Keywords: <i>Tithonia diversifolia, Asteraceae, sesquiterpine</i> lactone, 8-(2-methylbutanoyl)-3, 10 Epoxy-3, 8-dihydroxyl-4, 11 (13)- germacradien-12, 6-olide, Malaria

Abstract

Tithonia diversifolia (Hemsl.) A. Gray is known to contain sesquiterpene lactones and related compounds. A new sesquiterpine lactone 8-(2-methylbutanoyl)-3, 10 Epoxy-3, 8-dihydroxyl-4, 11 (13)- germacradien-12, 6-olide was isolated from the aerial part of the plant. The structure was established by spectroscopic methods.
Key words: Tithonia diversifolia, Asteraceae, sesquiterpine lactone, 8-(2-methylbutanoyl)-3, 10 Epoxy-3, 8-dihydroxyl-4, 11 (13)- germacradien-12, 6-olide, Malaria
Nig. J. Nat. Prod. and Med. Vol.8 2004: 74-76
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