Blood Glucose Lowering Activities Of Seed Of Persea Americana On Alloxan Induced Diabetic Rats

Abstract

The n-hexane, chloroform and methanol extracts of Persea americana seeds obtained by cold maceration were assessed for blood glucose lowering activity using two doses of alloxan. The different extracts caused significant blood glucose lowering effect than the glibenclamide in the single dose alloxanized rats but in the double dose alloxanized rats, the glibenclamide showed more significant blood glucose lowering effect than the extracts. P.americana can lower blood glucose levels in mild hyperglycemia but not in severe hyperglycemia.

Keywords: Persea americana, Lauraceae, hyperglycemia, alloxan-induced diabetes

Nigerian Journal of Natural Products and Medicine Vol. 11 2007 pp. 26-28