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Early Diagnosis of Posttraumatic Deep Vein Thrombosis - A Review
Abstract
OBJECTIVE: The importance of early diagnosis and treatment of deep vein thrombosis in patients with fractures of long bones
INTRODUCTION: Associated injury to deep-veins in limb fractures presents a serious pathology. It results not only to localized venous occlusion but also to death from pulmonary embolism. Thrombosis of deep-veins occurs in 24.5-80 percent of patients with fractures and soft tissue injuries of the limb 1-4. Several studies have detailed the changes that take place in blood vessels, noting vascular damage, blood stagnation and hypercoagulation as the major causes of deep vein thrombosis. Damage to the endothelium results in activation of platelets and coagulation, while damage to collateral channels increases plasma infiltration, swelling and ischaemia.
CONCLUSION: We conclude that despite the high interest shown in the study of this pathology, the great strides made in the past in our understanding of the natural history, prophylaxis and treatment of the disease, its early diagnoses remains a difficult clinical problem. There is need for early diagnosis of deep vein thrombosis to reduce morbidity and mortality from postphlebitic syndrome and pulmonary embolism
Nig Jnl Orthopaedics & Trauma Vol.2(2) 2003: 65-67
INTRODUCTION: Associated injury to deep-veins in limb fractures presents a serious pathology. It results not only to localized venous occlusion but also to death from pulmonary embolism. Thrombosis of deep-veins occurs in 24.5-80 percent of patients with fractures and soft tissue injuries of the limb 1-4. Several studies have detailed the changes that take place in blood vessels, noting vascular damage, blood stagnation and hypercoagulation as the major causes of deep vein thrombosis. Damage to the endothelium results in activation of platelets and coagulation, while damage to collateral channels increases plasma infiltration, swelling and ischaemia.
CONCLUSION: We conclude that despite the high interest shown in the study of this pathology, the great strides made in the past in our understanding of the natural history, prophylaxis and treatment of the disease, its early diagnoses remains a difficult clinical problem. There is need for early diagnosis of deep vein thrombosis to reduce morbidity and mortality from postphlebitic syndrome and pulmonary embolism
Nig Jnl Orthopaedics & Trauma Vol.2(2) 2003: 65-67
