Compliance of a Secondary Health Facility to the Nigerian Antimalarial Treatment Policy

  • VU Odili
  • BC Okupa
  • HA Okeri
  • AW Udezi

Abstract

In Nigeria, the change from chloroquine and other antimalarial monotherapy treatment to artemisininbased combination therapy (ACT) was introduced in 2004 due to evidence-based national and international findings. This one-year retrospective study describes the level of compliance to the national antimalarial treatment policy in our health institutions using the Central Hospital, Sapele in Delta State as a case study. Records of antimalarial prescriptions as well as patient biodata were systematically collected using a data form. A total of two hundred and fifty prescriptions on case management of malaria from January to December 2005 were randomly selected such that the prescribing habit of a cross section of the clinicians was obtained. Artemisinin based combination drugs were the most frequent antimalarials prescribed, they accounted for 73(28.2%) of the total antimalarial prescription. This was closely followed by artemisinin monotherapy 66(25.4%), others were chloroquine 56(21.6%), quinine 46(17.7%), sulphadoxine/pyrimethamine (SP) 14(5.4%) and halofantrine 7(2.7%). Chloroquine and quinine were still the drugs of choice in treating malaria in pregnancy. The level of compliance of the doctors in this health facility to the national anti-malarial treatment policy was quite low and various antimalarial monotherapies including chloroquine were still being used as first line drugs for malaria treatment.

Keywords: Antimalarials, guidelines, treatment policy

Nigerian Journal of Pharmaceutical Research, Vol. 8 No 1 pp. 72 - 77 (September 2010)

Author Biographies

VU Odili
Department of Clinical Pharmacy and Pharmacy Practice, Faculty of Pharmacy, University of Benin, Benin-City, Nigeria
BC Okupa
Department of Clinical Pharmacy and Pharmacy Practice, Faculty of Pharmacy, University of Benin, Benin-City, Nigeria
HA Okeri
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Benin, Benin-City, Nigeria
AW Udezi
Department of Clinical Pharmacy and Pharmacy Practice, Faculty of Pharmacy, University of Benin, Benin-City, Nigeria
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