On Vitro Activity Of Pefloxacin And Other Antibiotics Against Grm Negative Bacteria in Ibadan, Nigeria

Abstract

Gram negative organisms have continued to generate much interest in bacterial infections in the university College Hospital, Ibadan (UCH), because most of them are multiple drug resistant, and are resistant to many antibiotics available.



The present study confirms an increasing percentage of common isolate resistant to Gentamacin, Augmentin and Azithromicin. Pefloxacin (Abaktal), a new generation guinolong and Ofloxacin showed strong activity against all isolates tested with MIC values within the range of those reported as sensitive from many overseas centres.



Pefloxacin is valuable antibiotic for treatment of severe infection in our environment.

Nigerian Quarterly Journal of Hospital Medicine Vol. 9, No. 1 (1999) pp. 54-57