PROMOTING ACCESS TO AFRICAN RESEARCH

Nigerian Quarterly Journal of Hospital Medicine

Log in or Register to get access to full text downloads.

Remember me or Register



DOWNLOAD FULL TEXT Open Access  DOWNLOAD FULL TEXT Subscription or Fee Access

Effects Of Cissus Populnea (Ogbolo) On Mainstream Smoked Weaned Rabbit

H A Smith, O Ogunfeibo

Abstract




The effect of Cissus populnea, a medicinal plant commonly used by the Nigerian Traditional medicine practitioners for the treatment of tertiary abnormalities especially in male has been investigated in smoking maturing male rabbits (1.0 -1.5kg BW). It was found that daily exposure to mainstream (M) smoke for 40 minutes produced significant reduction in sperm concentration (15.4± 2.5 (M) vs. 184± 3.6 (C) × 106 cells/ ml p<0.001; Testicular protein mg/ dl (4.06± 0.32 (M) vs 6.4± 0.8) p<0.01; (Motility 7.5± 7.3 (M) vs. 80± 3.5 (C); the other testicular parameters increased. Malonaldehyde m mol./ mg prot. (144 ± 3.11) (M) vs. 114 ± 2(C). Glutathione peroxidase activity (GSHPX) u/ mgprot.622 ± 16 (M) vs. 239.49 ± 15 (C) and alkaline phosphate u/ mg prot. (393 ± 24) (M) vs. 207.15 ± 19 (C) respectively. Except for malonaldehyde concentration that increased 10 fold in the presence of C. populnea, significant improvements in all other parameters were observed. Sperm concentration was 175% higher than that of (M); GSHPX activity reduced by 118% and alkaline phosphatase activity by 31% in the C. populnea treated group. The results suggested that treatment of mainstream cigarette smoked rabbits with C. populnea 200mg/ kg increased sperm concentration above the normal (20 × 106 cells ml), reduced testicular GSHPX and alkaline phosphatase activities when compared with untreated smoked rabbits.

NQJHM Vol. 15 (1) 2005: pp. 19-22



http://dx.doi.org/10.4314/nqjhm.v15i1.12747
AJOL African Journals Online