Postoperative analgesia in children when using clonidine in addition to fentanyl with bupivacaine given caudally

  • Anouar Jarraya
  • Sahar Elleuch
  • Jawhar Zouari
  • Mohamed Smaoui
  • Sofiene Laabidi
  • Kamel Kolsi

Abstract

The aim of the study was to evaluate the efficacy of clonidine in association with fentanyl as an additive to bupivacaine 0.25% given via single shot caudal epidural in pediatric patients for postoperative pain relief. In the present prospective randomized double blind study, 40 children of ASA-I-II aged 1-5 years scheduled for infraumblical surgical procedures were randomly allocated to two groups to receive either bupivacaine 0.25% (1 ml/kg) with fentanyl 1 μg/kg and clonidine 1μg/kg (group I) or bupivacaine 0.25% (1 ml/kg) with fentanyl 1 μg/kg (group II). Caudal block was performed after the induction of general anesthesia. Postoperatively patients were observed for analgesia, sedation, hemodynamic parameters, and side effects or complications.Both the groups were similar with respect to patient and various block characteristics. Heart rate and blood pressure were not different in 2 groups. Significantly prolonged duration of post-operative analgesia was observed in group I (P<0.05). Side effects such as respiratory depression, vomiting and bradycardia were similar in both groups. The adjunction of clonidine to fentanyl as additives to bupivacaine in single shot caudal epidural in children may provide better and longer analgesia after infraumblical surgical procedures.

The Pan African Medical Journal 2016;24

Author Biographies

Anouar Jarraya
Service d’Anesthésie Réanimation, Hôpital Hedi Chaker, Sfax, Tunisie
Sahar Elleuch
Service d’Anesthésie Réanimation, Hôpital Hedi Chaker, Sfax, Tunisie
Jawhar Zouari
Service d’Anesthésie Réanimation, Hôpital Kremlin, Bicêtre
Mohamed Smaoui
Service d’Anesthésie Réanimation, Hôpital Hedi Chaker, Sfax, Tunisie
Sofiene Laabidi
Service d’Anesthésie Réanimation, Hôpital Hedi Chaker, Sfax, Tunisie
Kamel Kolsi
Service d’Anesthésie Réanimation, Hôpital Hedi Chaker, Sfax, Tunisie
Published
2016-09-18
Section
Articles

Journal Identifiers


eISSN: 1937-8688