A three-year-old boy with hypodipsic hypernatremia syndrome

  • Bousayna Iraqi
  • Rachid Abilkassem
  • Nezha Dini
  • Aomar Agadr
Keywords: brain calcifications, child, hypodipsic hypernatremia syndrome

Abstract

We describe a three-year-old boy who had a growth and psychomotor retardation associated with inappropriate lack of thirst and vasopressin secretion in the presence of chronic plasma hyperosmolarity. Computed brain tomography revealed bilateral supratentorial sub-ependymal and cortical calcifications. Dissociation in the plasma vasopressin response to osmotic change was demonstrated in this patient. Treatment with a vasopressin analogue, desamino-D-arginine vasopressin (DDAVP) and forced intake of water restored plasma osmolality and serum sodium levels to normal.

Keywords: Brain calcifications, child, hypodipsic hypernatremia syndrome

Author Biographies

Bousayna Iraqi
Department of Paediatrics, Mohammed V Military Hospital, Mohammed V University, Rabat, Morocco
Rachid Abilkassem
Department of Paediatrics, Mohammed V Military Hospital, Mohammed V University, Rabat, Morocco
Nezha Dini
Department of Paediatrics, Mohammed V Military Hospital, Mohammed V University, Rabat, Morocco
Aomar Agadr
Department of Paediatrics, Mohammed V Military Hospital, Mohammed V University, Rabat, Morocco
Published
2019-02-18
Section
Articles

Journal Identifiers


eISSN: 1937-8688