Department of Public Health and Infectious Diseases, Sapienza University of Rome, Policlinico Umberto I, Rome, Italy

  • Vita Serena Migrant Health Research Organisation (Mi-HeRO)-Centro di Ricerca Sulla Salute delle Popolazioni Mobili e Globale, Italy; Department of Public Health and Infectious Diseases, Sapienza University of Rome, Policlinico Umberto I, Rome, Italy
  • Miglietta Alessandro Units of Epidemiology and Preventive Medicine, Central Tuscany Health Authority, Florence, Italy, Italy
  • Lopalco Maurizio Sanitary Bureau of Asylum Seekers Center of Castelnuovo di Porto, Rome, Italy; Auxilium Società Cooperativa Sociale, Senise (PZ), Italy
  • Terrazzini Nadia School of Pharmacy and Biomolecular Sciences, University of Brighton, United Kingdom
  • Sargentini Valeria Clinical Pathology, Department of Experimental Medicine, Sapienza University of Rome, Italy
  • Cella Eleonora Unit of Medical Statistics and Molecular Epidemiology, University Campus Bio-Medico of Rome, Italy
  • Bachetoni Alessandra Clinical Pathology, Department of Experimental Medicine, Sapienza University of Rome, Italy
  • Dicuonzo Giordano Clinical Pathology and Microbiology Laboratory, University Hospital Campus Bio-Medico of Rome, Italy
  • Angeletti Silvia Clinical Pathology and Microbiology Laboratory, University Hospital Campus Bio-Medico of Rome, Italy
  • Ciccozzi Massimo Unit of Medical Statistics and Molecular Epidemiology, University Campus Bio-Medico of Rome, Italy
  • Ceccarelli Giancarlo Migrant Health Research Organisation (Mi-HeRO)-Centro di Ricerca Sulla Salute delle Popolazioni Mobili e Globale, Italy; Department of Public Health and Infectious Diseases, Sapienza University of Rome, Policlinico Umberto I, Rome, Italy
Keywords: Haematological reference range; Malian adults; sub-saharan migrants

Abstract

Introduction: haematological reference values are very important for diagnostic orientation and treatment decision. The aim of this study was to establish haematological reference values for Malian healthy adults.

Methods: a cross-sectional study including 161 male Malians aged between 19 and 54 years old was performed. Median and reference ranges were calculated for haematological and biochemical parameters. Parametric student's t-test was used to determine any statistically significant differences by age, smoker status, body mass index (BMI) and occupation. Ranges were further compared with those reported for other African, Afro-American and Caucasian populations.

Results: increased levels of MCV, MCH, PLT and EOS were found in younger Malians who had abnormal BMI and altered platelets parameters. Notably, significantly lower eosinophil and monocyte counts were observed in Malians compared to Europeans The smoking status did not seem to directly affect RIs.

Conclusion: this is the first study to determine normal laboratory parameters in Malian adult males. Our results underscore the necessity of establishing region-specific clinical reference ranges that would allow clinicians and practitioners to manage laboratory tests, diagnosis and therapies. These data are useful not only for the management of patients in Mali, but also to support European and American clinicians in the health management of asylum seekers and migrants from Mali.

Published
2019-01-04
Section
Articles

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eISSN: 1937-8688