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Published:
Aug 18, 2020Keywords:
Chronic hepatitis B infection; hepatocellular carcinoma; pregnancy
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Hepatitis B-related hepatocellular carcinoma in a 36-year-old pregnant woman: prognosis and management dilemma
Abstract
Management of chronic hepatitis B infection
complicated by hepatocellular carcinoma (HCC) in
pregnancy poses a treatment dilemma as the
pregnancy accelerates disease progression and
narrows the diagnostic tools and therapeutic
choices. Studies have reported higher maternal
and fetal losses. We share our experience with a
36-year-old pregnant woman who presented at 35
weeks' gestation with a large painful nodular liver
and significant weight loss. She tested HBsAgpositive and had both clinical and laboratory
features of severe liver decompensation. The
abdominal ultrasound rightly described HCC on a
cirrhotic background. The fetus was delivered by
cesarean section but the mother died soon after.
