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The prognostic impact of the CALLY index in trauma patients in the emergency department: A retrospective observational study


Abstract

This retrospective observational study included 550 trauma patients admitted to the emergency department of Esenyurt Necmi Kadıoğlu State Hospital between January 2023 and December 2024. Patients' clinical and laboratory data were reviewed. The primary outcomes were in-hospital mortality, intensive care unit (ICU) admission, and hospital length of stay. Statistical analyses included logistic regression, subgroup analysis, and receiver operating characteristic (ROC) curve analysis. A p-value of <0.05 was considered statistically significant. Patients with a lower CALLY index had significantly higher in-hospital mortality (25% vs. 8%) and ICU admission rates (45% vs. 18%) compared to those with higher CALLY values. A CALLY index below 5.2 was identified as the optimal cut-off for predicting poor outcomes (AUC = 0.78). The index also showed a negative correlation with hospital length of stay and outperformed conventional inflammatory markers such as CRP and NLR in prognostic accuracy. The CALLY index is a simple, accessible, and effective biomarker for predicting mortality and ICU needs in trauma patients. It may support early clinical decision-making in emergency settings. Further multicenter prospective studies are warranted to validate its broader applicability.


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eISSN: 2707-2800