Laboratory evaluation of commercial interferon preparations

  • B.D. Schoub
  • S. F. Lyons
  • M. Crespi
  • M.-N. Chiu
  • R. Lomnitzer

Abstract

The antiviral, antiproliferative and natural killer-cell (NKC) stimulatory activities of four commercial therapeutic interferon preparations were assayed in our laboratory. The antiviral and antiproliferative activities of each preparation were relatively similar, but an unexpectedly high NKC stimulatory activity was foupd in one ofthem. In-house determination of antiviral activity and evaluation of the antiprolifera'tive and NKC stimulation potential of-"interferon preparations are. essential before rational clinical trials of this agent are carried out.

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eISSN: 0256-95749
print ISSN: 2078-5135