The dilemma of the creatine kinase cardiospecific iso-enzyme (CK-MB) in marathon runners

  • T. H. Diamond
  • R. Smith
  • A. P. Goldman
  • D. P. Myburgh
  • J.M. Bloch
  • F Visser

Abstract

Serum creatine kinase iso-enzyme (CK-MB) levels were measured in 51 marathon runners before and after a 50 km marathon event. Ninety-five per cent of the runners were found to have pathologically elevated values, i.e. CK-MB concentrations were elevated to the range normally considered indicative of myocardial necrosis. Results indicate that a rise in theCK-MB level is common after marathon running. We therefore believe that cardiac enzymes are an unreliable indicator of myocardial infarction in patients who experience chest pain following strenuous muscular exercise.

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eISSN: 0256-95749
print ISSN: 2078-5135