The dilemma of the creatine kinase cardiospecific iso-enzyme (CK-MB) in marathon runners

  • T. H. Diamond
  • R. Smith
  • A. P. Goldman
  • D. P. Myburgh
  • J.M. Bloch
  • F Visser


Serum creatine kinase iso-enzyme (CK-MB) levels were measured in 51 marathon runners before and after a 50 km marathon event. Ninety-five per cent of the runners were found to have pathologically elevated values, i.e. CK-MB concentrations were elevated to the range normally considered indicative of myocardial necrosis. Results indicate that a rise in theCK-MB level is common after marathon running. We therefore believe that cardiac enzymes are an unreliable indicator of myocardial infarction in patients who experience chest pain following strenuous muscular exercise.


Journal Identifiers

eISSN: 0256-95749
print ISSN: 2078-5135