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Chlorpromazine, Clotiapine and Thioridazine- A C10mparative Clinical Trial on Bantu Psychotic Patients
Abstract
In a non-blind assessment of 3 neuroleptic drugs, chlorpromazine (Largactil), thioridazine (Melleril) and clotiapine (Etomine), we found Etomine to be the drug of choice when the diagnosis is in doubt between a toxic psychosis or schizophrenia. This drug also offered the highest discharge rate, 77'7% at 12 weeks compared with 73'5% in the thioridazine group, and 55'5% in the chlorpromazine group. No clouding of consciousness was seen in the clotiapine group, whereas it was troublesome in the chlorpromazine group in patients having received high parenteral doses.
